Drug Resistance During HIV Pre-Exposure Prophylaxis
نویسندگان
چکیده
منابع مشابه
HIV pre-exposure prophylaxis in injecting drug users.
2060 www.thelancet.com Vol 381 June 15, 2013 Globally, there are an estimated 15·9 million injecting drug users, 3 million of whom have HIV. The illicit nature of injection drug use and associated social stigma have created substantial challenges for HIV prevention in this group. Despite these obstacles, several programmes have shown that HIV transmission in injecting drug users can be prevente...
متن کاملHIV-1 drug resistance resulting from antiretroviral therapy far exceeds that from pre-exposure prophylaxis.
TO THE EDITOR—We challenge the conclusions drawn by Hurt et al in their Viewpoint article " Pre-exposure Prophy-laxis and Antiretroviral Resistance: HIV Prevention at a Cost? " The authors cite the very few cases of human immunode-ficiency virus (HIV) drug resistance that have occurred in seroconverters from trials of pre-exposure prophylaxis (PrEP) as evidence of the potential for PrEP to jeop...
متن کاملPre-Exposure Prophylaxis for HIV Prevention.
c ase vignet tes The first patient, a 46-year-old sexually active man who has sex with men, presents for routine primary care. He lives in New York City and reports that he is in a long-term, stable, open relationship with a male partner and that he has had multiple recent sexual encounters with acquaintances. A recent HIV test was negative. He has seasonal allergies, for which he occasionally ...
متن کاملHIV pre-exposure prophylaxis for women
Women and girls comprise nearly half of HIV-infected individuals globally and 20% of new infections in the United States, indicating an urgent need to optimise HIV prevention options in this population. HIV pre-exposure prophylaxis (PrEP) - where antiretrovirals are administered to HIV-non-infected individuals at risk of HIV acquisition - is a promising, female-controlled HIV prevention strateg...
متن کاملAntiretroviral therapy and pre-exposure prophylaxis: combined impact on HIV transmission and drug resistance in South Africa.
BACKGROUND The potential impact of antiretroviral therapy (ART) and pre-exposure prophylaxis (PrEP) with overlapping and nonoverlapping antiretrovirals (ARVs) on human immunodeficiency virus (HIV) transmission and drug resistance is unknown. METHODS A detailed mathematical model was used to simulate the epidemiological impact of ART alone, PrEP alone, and combined ART + PrEP in South Africa. ...
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ژورنال
عنوان ژورنال: Drugs
سال: 2019
ISSN: 0012-6667,1179-1950
DOI: 10.1007/s40265-019-01108-x